EC Number   |
Reaction |
Reference |
|---|
   3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
- |
- |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
active site, Arg498, Glu258, Tyr317, and Tyr262 are catalytic residues, with the aromatic ring of the latter being important for function |
-, 656428 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
catalytic chemistry involves the formation of a covalent intermediate with an active site tyrosine nucleophile |
665732 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
catalytic mechanism, overview |
717641 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
enzyme does not act on 4-O-acetylated sialic acids |
655256 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
exo-glycosidase |
-, 655515 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
exo-glycosidase, active center contains essential cysteine residues |
655515 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
exo-glycosidase, the active center contains essential cysteine residues |
655515 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
ping-pong bi-bi kinetic mechanism. Residue D59 functions as acid/base catalyst, and Y342 as active site nucleophile |
696254 |
| 3.2.1.18 | colominic acid + H2O = sialic acid + lactose |
reaction and kinetic mechanisms |
655779 |
