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EC Number Reaction Commentary Reference
Show all pathways known for 2.7.6.5Display the word mapDisplay the reaction diagram Show all sequences 2.7.6.5ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate bifunctional enzyme, additionally has polynucleotide phosphorylase activities 642777
Show all pathways known for 2.7.6.5Display the word mapDisplay the reaction diagram Show all sequences 2.7.6.5ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate GDP can also act as acceptor -
Show all pathways known for 2.7.6.5Display the word mapDisplay the reaction diagram Show all sequences 2.7.6.5ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate the catalytic pathway of (p)ppGpp synthesis involves a sequentially ordered substrate binding, activation of ATP in a strained conformation, and transfer of diphosphate through a nucleophilic substitution (SN2) reaction. pppGpp, but not ppGpp, positively regulates the enzyme at an allosteric site -, 739546
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