EC Number |
Reaction |
Reference |
---|
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
active site structure |
638166, 638168, 638171 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
catalytic site: amino acid residues 106-108 |
638171 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
forward reaction follows a random bi-bi mechanism |
638167 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
mechanism |
638165, 638168 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
molecular reaction mechanism in both directions of the reaction for hAPRT: in the forward reaction, SN2-type molecular mechanism including some SN1 characteristics, and in the reverse reaction, a proposed magnesium-assisted SN2-type mechanism, detailed overview |
759493 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
ordered bi-bi mechanism, kinetics |
638164 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
ping-pong mechanism |
638147 |
2.4.2.7 | AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate |
the enzyme with reversible activities has an ordered sequential bibi reaction mechanism |
759017 |