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EC Number Reaction Commentary Reference
Display the reaction diagram Show all sequences 2.4.1.2923 UDP-N-acetyl-alpha-D-galactosamine + GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-tritrans,heptacis-undecaprenol = 3 UDP + [GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-PP-tritrans,heptacis-undecaprenol - -
Display the reaction diagram Show all sequences 2.4.1.2923 UDP-N-acetyl-alpha-D-galactosamine + GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-tritrans,heptacis-undecaprenol = 3 UDP + [GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-PP-tritrans,heptacis-undecaprenol PglH might follow a SN1-like mechanism, where the nucleophilic attack from the acceptor substrate and the departure of the leaving UDP occur from the same side. This would require the leaving group to act as a catalytic base to activate the incoming nucleophile. Glycan counting mechanism during PglH reaction, overview 759837
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