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EC Number Reaction Commentary Reference
Show all pathways known for 2.4.1.182Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.182a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a lipid X = UDP + a lipid A disaccharide - -
Show all pathways known for 2.4.1.182Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.182a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a lipid X = UDP + a lipid A disaccharide enzyme LpxB catalyzes the nucleophilic attack of the 6'-hydroxyl of lipid X (1) on the anomeric carbon of UDP-DAG (2) with UDP as the leaving group. As for other inverting GT-B enzymes, this reaction is thought to proceed by an SN2 mechanism 759836
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