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Results 1 - 10 of 17 > >>
EC Number Reaction Commentary Reference
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 - -
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 active site structure a catayltic triad of Cys-His-Asn residues 665474
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 active site structure and catalytic reaction mechanism, T97, R46, W42, C122, R161, H258, and N289 are important for activity, structure-function relationship -, 659493
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 active site structure contains a catalytic triad of His249-Asn279-Cys112 residues 486939
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 active site structure with a CoA/malonyl-ACP-binding channel leading from the enzyme surface to the buried active site Cys residue, a second channel leads from the active site to the surface with a threonine residue controlling the passage of longer acyl chains 665477
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 catalytic reaction mechanism for decarboxylation and condensation -, 659724
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 catalytic reaction mechanism might include a water molecule or a hydroxyl anion in Cys112 deprotonation, large conformational changes in the active site e.g. through disordering of four essential loops and the movement of the two catalytic residues Cys112 and His244 666011
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 catalytic reaction mechanism via a tetrahedral transition state, active site structure contains an oxyanion hole and a tunnel, catalytic residues are Cys112, His244, and Asn274, which are all required for condensation activity of the enzyme, additionally His244 and Asp274 are required for decarboxylation, Cys112 is essential for transacylation, overview 666950
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 catalytic residues are Cys112, His244, and Asn274, catalytic reaction mechanism includes acetylation of Cys112 in the primer binding pocket, structure and reaction mechanism modeling 665472
Show all pathways known for 2.3.1.180Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.180acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2 catalytic residues are Cys123, His323, and Asn353 666668
Results 1 - 10 of 17 > >>