EC Number |
Reaction |
Reference |
---|
1.3.1.70 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ |
determination of residues critical for activity, overview |
656798 |
1.3.1.70 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ |
mechanism |
-, 288493, 288495 |
1.3.1.70 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ |
reduction of 14-double bond of conjugated DELTA8,14-sterols and DELTA7,14-sterols |
288490, 288491 |
1.3.1.70 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ |
regulation, regulatory mechanism, enzyme induction and suppression, dietary induction |
288491 |
1.3.1.70 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ |
residues G225, Y317, and E475 are not essential for activity |
656304 |
1.3.1.70 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ |
this enzyme acts on a range of steroids with a 14(15)-double bond |
- |