EC Number   |
Reaction |
Reference |
|---|
    1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
- |
- |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
catalytic mechanism with the first step involving oxidative addition of superoxide to form a ferric-peroxo intermediate. The Fe spin state and the trans cysteinate ligand play an important role in effecting superoxide reduction and peroxide release |
723617 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
enzyme active site structure and mechanism |
686522 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
enzyme active site structure and mechanism, catalytic cycle involving iron complexes, overview |
686523 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
enzyme active site structure and mechanism, proposed mechanism for SOR-catalyzed reduction of superoxide via hydroperoxo and solvent-bound intermediates, catalytic cycle involving iron complexes, overview |
684111 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
FITR study, presence of E47 is important for the structural reorganization accompanying iron oxidation, catalytic role of K48 is purely electrostatic, guiding superoxide toward the reduced iron |
657916 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
in absence of O2.-, reduction potential and absorption spectrum of the iron center II exhibit a pH transition. First reaction intermediate is an iron(III)-peroxo species, second intermediate is an iron(III)-hydroperoxo species |
658089 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
presence of Fe(NHis)4(SCys) site is sufficient to catalyze reduction of the intracellular superoxide to nonlethal levels |
660350 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
reaction mechanism involves the diffusion-limited encounter of superoxide with the reduced iron site and concomitant formation of an Fe3+-(hydro)peroxo adduct that, upon protonation, leads to the formation of hydrogen peroxide. By the end of this process, a glutamate residue coordinates the ferric ion, acting as a sixth ligand |
687820 |
| 1.15.1.2 | superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin |
reaction mechanism of SOR involving transfer of an electron and two protons to superoxide to form hydrogen peroxide, kinetic mechanism, detailed overview |
687278 |
