EC Number |
Reaction |
Reference |
---|
1.1.1.53 | androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ |
catalytic residues are Ser114, Tyr127, and Lys131 |
687870 |
1.1.1.53 | androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ |
deduced reaction mechanism from crystal structure model |
287110 |
1.1.1.53 | androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ |
exhibits carbonyl reductase-like activity |
287107 |
1.1.1.53 | androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ |
exhibits carbonyl reductase-like activity, 85% amino acid sequence homology with human carbonyl reductase |
287106 |
1.1.1.53 | androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ |
exhibits in male rat liver microsomes also a carbonyl reductase-like activity with acetohexamide as substrate |
287101, 287102 |