Refine search

Search Reaction

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 6 of 6
EC Number
Reaction
Commentary
Reference
ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
catalysis of a SN2 reaction through hydrogen bonding of the liberated oxygen-5' to the histidine, charge neutralization by the two Mg2+ ions, and stabilization of the product sulfonium cation through a close, non-bonded, contact between the sulfur and the ribose oxygen-4'
ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
mechanism
ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
mechanism of inhibiton by product analogues and implications for reaction
ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
mechanism, key role of K182 in the correct positioning of the substrates, and D135 in stabilizing the sulfonium group formed in the product
ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
neutral H14 acts as an acid to cleave the C5-O5 bond of ATP, S of methionine makes a nucleophilic attack on the C5 to form the product
ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
steady state ordered Bi Ter mechanism with ATP adding before L-methionine and S-adenosylmethionine being the first product released, random release of phosphate and diphosphate
Results 1 - 6 of 6