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Results 1 - 9 of 9
EC Number
Reaction
Commentary
Reference
(S)-dihydroorotate + fumarate = orotate + succinate
A flavoprotein (FAD, FMN). Ferricyanide can act as accetor; light
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(S)-dihydroorotate + fumarate = orotate + succinate
cysteine and serine are active site base residues. One-site ping-pong mechanism with fumarate as electron acceptor
(S)-dihydroorotate + fumarate = orotate + succinate
light sensitivity seems to result in a conformational change and a partial loss of enzymatic activity
(S)-dihydroorotate + fumarate = orotate + succinate
mechanism, pyrimidine biosynthetic pathways
(S)-dihydroorotate + fumarate = orotate + succinate
ping-pong bi-bi mechanism
(S)-dihydroorotate + fumarate = orotate + succinate
ping-pong mechanism
(S)-dihydroorotate + fumarate = orotate + succinate
sulfhydryl groups suggested to be located near the active site, suggested that enzyme produces superoxide free radicals upon reaction with oxygen
(S)-dihydroorotate + fumarate = orotate + succinate
the active site contains a water filled cavity buried beneath a highly conserved and flexible loop. Orotate is bound by four conserved asparagine side chains. Implications for differences in substrate binding and in the catalytic mechanism between the different enzyme families are given
(S)-dihydroorotate + fumarate = orotate + succinate
two-site ping-pong mechanism, catalytic base is serine
Results 1 - 9 of 9