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EC Number Reaction Commentary Reference
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ active site structure -, 671075
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ highly conserved active site structure, active site residues Asp157, Glu159, and Glu241, residue His219 is essential for placing the substrate in the active site for optimal catalysis 675038
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ mechanism 286427
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ random ordered mechanism, though binding of NADPH first is preferential at 0.2 mM due to its low Km. Conformational equilibrium between a predominant, inactive open form and a minor, active closed form of the unliganded enzyme, overview 724374
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ random substrate binding and ordered release of NADP+ followed by partially rate-limiting release of 2-C-methyl-D-erythritol 4-phosphate, transient generation of MtDXR-NADPH-MEP ternary complex, kinetic analysis and modeling, overview 724346
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ reaction mechanism 675577
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ reaction mechanism via 2-C-methylerythrose 4-phosphate intermediate 672538
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ retro-aldol/aldol mechanism 684434
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ steady-state random mechanism 654748
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2672-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ stereochemistry 286421
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