EC Number   |
Posttranslational Modification |
Reference |
|---|
    4.1.1.9 | more |
INS-1 MCD, sequence shows multiple possible sites of phosphorylation by casein kinase II and protein kinase C, no acylation sites |
649668 |
| 4.1.1.9 | more |
recombinant MCD has a different degree or lack of glycosylation from the original rat enzyme |
651828 |
| 4.1.1.9 | more |
the enzyme is phosphorylated at seven seryl/threonyl residues, and is acetylated at 11 lysyl residues |
681625 |
| 4.1.1.9 | phosphoprotein |
activation of AMP-activated protein kinase during muscle contraction leads to phosphorylation of MCD and an increase in its activity |
652024 |
| 4.1.1.9 | phosphoprotein |
phosphorylated at Ser-204 and Tyr-405 |
746899 |
| 4.1.1.9 | proteolytic modification |
full-length MCD contains a putative, N-terminal 39 amino acid mitochondria targeting sequence and a peroxisomal tageting sequence |
653773 |
| 4.1.1.9 | proteolytic modification |
the 50.7 kDa isoform may be generated from the 54.7 kDa isoform by posttranslational processing, probably by N-terminal cleavage |
649690 |
| 4.1.1.9 | proteolytic modification |
the N-terminal 38 amino acids represents a putative mitochondrial targeting sequence, the last 3 amino acid sequences, SKL, represent peroxisomal targeting ones |
651828 |
