EC Number   |
Posttranslational Modification |
Reference |
|---|
   3.4.21.B48 | no glycoprotein |
- |
-, 651844 |
| 3.4.21.B48 | proteolytic modification |
pro-kumamolisinS278A: the prodomain exhibits a half-beta sandwich core docking to the catalytic domain similarly as the equivalent subtilisin prodomain complexes |
-, 653914 |
| 3.4.21.B48 | proteolytic modification |
the enzyme is synthesiszed as a larger precursor consisting of two regions: amino-terminal prepro (199 amino acids) and mature proteins (384 amino acids) |
-, 651795 |
| 3.4.21.B48 | proteolytic modification |
the enzyme needs to be cleaved in to the mature enzyme and the N-terminal prepropeptide, autocatalytic cleavage |
-, 664913 |
| 3.4.21.B48 | proteolytic modification |
the enzyme needs to cleaved in to the mature enzyme and the N-terminal prepropeptide, autocatalytic cleavage |
-, 665094 |
| 3.4.21.B48 | proteolytic modification |
the enzyme performs autoactivation, autocatalytic process of pro-kumamolisin activation, the protonation of Asp164 triggers conformational changes and generates the functional active site for autocatalysis, mechanism of acylation for autocatalytic cleavage of prodomain, molecular dynamics and quantum mechanical/molecular mechanical free-energy simulations, overview |
-, 731647 |
