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EC Number Posttranslational Modification Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein activation by phosphorylation 490796
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein autophosphorylation in presence of Mg2+ 762174
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein DETA/NO and streptozotocin induce rapid threonine phosphorylation of MEKK-1, overview 686415
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein ERK and MEK are activated by phosphorylation 666399
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein MEK and ERK are activated by phosphorylation 663988
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein MEK and ERK are phosphorylated by B-Raf, a mitogen-activated protein kinase kinase kinase, the B-Raf mutant V590E activates the enzymes constitutively and independently of Ras, which leads to melanoma cell proliferation 665489
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein MEK is phosphorylated and activated by the mitogen-activated protein kinase kinase kinase COT, which can be inhibited by p105 663773
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein MEK is phosphorylated at Ser217 and Ser221, activating phosphorylation of ERK-1 and ERK-2 at Thr202 and Tyr204 induced by tetanus toxin or the C-terminal part of the heavy chain 663925
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein MKKK20 phosphorylates MKK3 761176
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2phosphoprotein MKKs are activated by phopshorylation through MKKKs, e.g. MEKK, MLK, TAK1, Ask1, or TPL2 682214
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