EC Number |
Posttranslational Modification |
Reference |
---|
2.7.11.21 | phosphoprotein |
- |
682562, 703030, 703598, 704101, 705868, 706088 |
2.7.11.21 | phosphoprotein |
autophosphorylation |
705620 |
2.7.11.21 | phosphoprotein |
Cdc5 function is regulated by sequential Cdk1 phosphorylation initially mostly at T242 and T238. Initial phosphorylation at T242 activates Cdc5 promotes Cdc14 release , and phosphorylation at T70 contributes to Cdc5-MEN function |
740273 |
2.7.11.21 | phosphoprotein |
phosphorylated by Aurora A |
703107 |
2.7.11.21 | phosphoprotein |
phosphorylation of threonine residues in the T-loop of the kinase domain is pivotal for PLKs activation. Phosphorylation of T238 site of Cdc5 is dispensable for cell viability |
740272 |
2.7.11.21 | phosphoprotein |
Plo1 is phosphorylated at Ser402 in the stress response pathway, mechanism, phosphorylation is required for recruitment to the interphase spindle pole body and mitotic entry for cell tip growth and cell division, Plo1 phosphorylation is increased at elevated temperature |
662946 |
2.7.11.21 | phosphoprotein |
self-phosphorylation at multiple sites is required for Plk4 instability, indicating a requirement for a threshold level of Plk4 kinase activity to promote its own destruction |
728023 |
2.7.11.21 | phosphoprotein |
the active enzyme form is phosphorylated at tyrosine 210 |
760980 |
2.7.11.21 | phosphoprotein |
the enzyme is activated by phosphorylation of Thr210 by protein phosphatase 1 |
762085 |
2.7.11.21 | phosphoprotein |
the enzyme is phosphorylated by Chk2 |
662999 |