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EC Number Posttranslational Modification Commentary Reference
Show all pathways known for 2.4.1.122Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.122more itraconazole is a C1GALT1 inhibitor that directly binds C1GALT1 and promotes its proteasomal degradation, leading to significant blockade of C1GALT1-mediated effects in HNSCC cells in vitro and in vivo 759872
Show all pathways known for 2.4.1.122Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.122more the effect of itraconazole on C1GALT1 protein levels might be through posttranslational modifications, analysis of mechanism by which itraconazole promotes C1GALT1 degradation 759356
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