EC Number   |
Posttranslational Modification |
Reference |
|---|
    2.3.1.24 | glycoprotein |
- |
754143 |
| 2.3.1.24 | glycoprotein |
Asn18, but not Asn285, of Lass6 is glycosylated, deglycosylation of Lass6 with PNGase F (N-glycosidase F). Lass6 is modified by N-glycosylation of a high-mannose and/or hybrid type. N-glycosylation is not essential for the dihydroceramide synthase activity of Lass6 |
752700 |
| 2.3.1.24 | glycoprotein |
the N-glycosylation of Lass5 appears as two bands, deglycosylation of Lass5 with PNGase F (N-glycosidase F) |
752700 |
| 2.3.1.24 | no glycoprotein |
- |
754143 |
| 2.3.1.24 | phosphoprotein |
isoform Cers2 is phosphorylated at the cytoplasmic C-terminal region. Treatment of cells with the casein kinase CK2-specific inhibitor CX-4945 lowers the phosphorylation level. Phosphorylation of CERS2 is important for its catalytic activity, acting mainly by increasing its Vmax value |
754143 |
| 2.3.1.24 | phosphoprotein |
isoform Cers2 is phosphorylated at the cytoplasmic C-terminalregion |
754143 |
| 2.3.1.24 | phosphoprotein |
isoform Cers3 is phosphorylated at the cytoplasmic C-terminal region. Treatment of cells with the casein kinase CK2-specific inhibitor CX-4945 does not lower the phosphorylation level. Treatment with lambda protein phosphatase reduces the activity by 28% |
754143 |
| 2.3.1.24 | phosphoprotein |
isoform Cers4 is phosphorylated at the cytoplasmic C-terminal region. Treatment with lambda protein phosphatase reduces the activity by 52% |
754143 |
| 2.3.1.24 | phosphoprotein |
isoform Cers5 is phosphorylated at the cytoplasmic C-terminal region. Treatment with lambda protein phosphatase reduces the activity by 27% |
754143 |
| 2.3.1.24 | phosphoprotein |
isoform Cers6 is phosphorylated by serine kinase CK2 at the cytoplasmic C-terminal region. Treatment with lambda protein phosphatase reduces the activity by 10% |
754143 |
