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EC Number Posttranslational Modification Commentary Reference
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3phosphoprotein bifunctional 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase associates with nucleoplasmin-anaplastic lymphoma kinase, and its phosphorylation requires anaplastic lymphoma kinase activity. Phosphorylation enhances enzymatic activity and dampens the methotrexate-mediated transformylase activity inhibition 696946
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