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EC Number Posttranslational Modification Commentary Reference
Show all pathways known for 4.4.1.20Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.20phosphoprotein phosphoregulation of LTC4S, as increased activity during MM6 cell differentiation correlates with reduced phosphorylation of 70-kDa ribosomal protein S6 kinase, which can phosphorylate purified LTC4S. The ribosomal protein S6 kinase inhibitor rapamycin at 20 nM doubles LTC4S activity of undifferentiated MM6 cells, and protein kinase A and C inhibitors H-89, CGP-53353, and staurosporine reverse the zymosan-induced suppression of LTC4S activity 714941
Show all pathways known for 4.4.1.20Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.20phosphoprotein residue Ser36 is the major p70S6k phosphorylation site, along with a low frequency site at Thr40 748212
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