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Results 1 - 3 of 3
EC Number Posttranslational Modification Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.4.4.2acetylation the activity is regulated by sequential posttranslational modifications, including acetylation and polyubiquitination, and reveal critical regulatory mechanisms of glycine metabolism and tumorigenesis. Acetylation of K514 inhibits glycine catabolism and pyrimidine synthesis. In addition, this acetylation of glycine decarboxylase also primes for its K33-linked polyubiquitination and proteasomal degradation, leading to suppression of glycine metabolism and tumorigenesis 765452
Display the word mapDisplay the reaction diagram Show all sequences 1.4.4.2proteolytic modification - 391998
Display the word mapDisplay the reaction diagram Show all sequences 1.4.4.2ubiquitination the activity is regulated by sequential posttranslational modifications, including acetylation and polyubiquitination (K33-linked polyubiquitination), and reveal critical regulatory mechanisms of glycine metabolism and tumorigenesis 765452
Results 1 - 3 of 3