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6.1.1.16
drug development
aminoacyl-tRNA synthetases are attractive targets for the discovery of antibacterial agents
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746197
6.1.1.16
medicine
in order to evaluate genetic associations between candidate genes involved in oxidative stress and multiple system atrophy (MSA) 119 Japanese patients with MSA and 123 controls are examined and single-nucleotide polymorphisms are genotyped. Results revealed genetic associations of cysteinyl-tRNA synthetase, solute carrier family 1A4, sequestosome 1, and eukaryotic translation initiation factor 4E-binding protein 1 with MSA
694292
6.1.1.16
molecular biology
Mycoplasmas hyopneumoniae are collected from bronchial alveolar lavage samples of infected pigs 28 days postinfection and compared to broth-grown cells using microarrays. During lung infection, the analysis indicates that 79 genes are differentially expressed. Of the down-regulated genes, 28 of 46 (61%) lacked an assigned function, in comparison to 21 of 33 (63%) of up-regulated genes. Cysteinyl-tRNA synthetase is down-regulated in vivo
692603
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