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EC Number Application Commentary Reference
Show all pathways known for 4.1.1.94Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.94medicine ECHDC1 expression is increased in gemcitabine-resistant bladder cancer cells, and is involved in their cell growth. Silencing of ECHDC1 significantly inhibits the proliferation of a gemcitabine-resistant UMUC-3-derived cell line. Silencing of ECHDC1 induces upregulation of p27, which is critical for cell cycle arrest in the G1 phase, and induces G1 arrest 748793
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