EC Number   |
Application |
Reference |
|---|
    4.1.1.33 | biofuel production |
enzyme establishes a possible route for biological production of petroleum based fuels and plastics by producing isobutene enzymatically |
707234 |
| 4.1.1.33 | drug development |
siRNAs targeting mevalonate (diphospho) decarboxylase (MVD) are found to inhibit Dengue virus replication in a stable A549 subgenomic Renilla replicon cell line (Rluc-replicon) and in naive A549 cells after dengue type 2 (DEN-2) New Guinea C (NGC) live virus infection, knock down of mevalonate (diphospho) decarboxylase can inhibit dengue viral replication |
706892 |
| 4.1.1.33 | medicine |
the upregulation of microRNA-214 and downregulation of mevalonate diphosphate decarboxylase transcription in the liver both play a role in the development of hypocholesterolemia in stroke-prone spontaneously hypertensive rats |
747312 |
| 4.1.1.33 | pharmacology |
the enzyme is an antibiotic target, since inhibition prevents the production of isopentenyl diphosphate |
704675 |
| 4.1.1.33 | synthesis |
Agrobacterium rhizogenes-mediated transformation and overexpression in Panax ginseng hairy roots leads to 4.4fold higher stigmasterol content and the accumulation of phytosterols and ginsenosides |
746600 |
