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EC Number Application Commentary Reference
Show all pathways known for 3.5.1.6Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.6medicine analysis of putative enzyme defects in patients with neurological disfunctions 172068
Show all pathways known for 3.5.1.6Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.6medicine mutation analysis in patients with cloned genes 172069
Show all pathways known for 3.5.1.6Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.6medicine pharmacogenetic studies in patients receiving fluoropyrimidine-based chemotherapy should include genetic variants in dihydropyrimidinase (DPYS) and beta-ureidopropionase (UPB1), in addition to DPYD, to improve the understanding of their contribution to severe toxicity from fluoropyrimidine-based chemotherapy. Potential unknown underlying causal variants linked to the associated dihydropyrimidinase and beta-ureidopropionase variants may have a clinically relevant effect on fluoropyrimidine toxicity and should be investigated 755001
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