Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Application

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 11 > >>
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine a single injection of ADAMTS5 siRNA induces the suppression of degradation in nucleus pulposus tissues 707311
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine ADAMTS-5 is the main aggrecanase in laryngeal squamous cell carcinoma presenting a stage-related increase up to stage III (8fold higher expression compared to normal), and thereafter decreased in stage IV. ADAMTS-5 is highly expressed by carcinoma cells. Within the cancerous and their corresponding macroscopically normal laryngeal tissues, an altered distribution and organization of multiple molecular forms (latent, activated and fragmented forms) of the enzymes is found 733436
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine ADAMTS5 is a biomarker for prediction of response to Infliximab in patients with rheumatoid arthritis 709707
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine design and development for potent and selective inhibitors of ADAMTS-4 and ADAMTS-5, which may be required for chronic osteoarthritis therapy 709044
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine overexpression of full-length ADAMTS5 suppresses B16 melanoma growth in mice. The reduced tumor growth is correlated with diminished tumor angiogenesis, together with reduced tumor cell proliferation and increased tumor cell apoptosis 733058
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine potential target for treatment of osteoarthritis 652268
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine stop progression of cartilage degradation in osteoarthritis by prevention of aggrecan cleavage via inhibition of aggrecanase 696674
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine the enzyme is a diagnostic marker in azoospermia 755570
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine the first thrombospondin type 1 repeat domain of ADAMTS5, unlike the second, has anti-angiogenic activities, ADAMTS5 is therefore an anti-angiogenic peptide and may serve as a prototype for future development into anti-cancer drugs 677997
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B12medicine therapeutic target in osteoarthritis 679302
Results 1 - 10 of 11 > >>