EC Number   |
Application |
Reference |
|---|
   3.4.24.26 | biotechnology |
A2 protease is usable for shrimp waste deproteinization in the process of chitin preparation, percent of protein removal after 3 h hydrolysis at 40°C with an enzyme/substrate ratio of 5 U/mg protein is about 75%. A2 proteolytic preparation also demonstrates powerful depilating capabilities of hair removal from bovine skin |
-, 717673 |
| 3.4.24.26 | diagnostics |
specific protease activity of the enzyme as indicator for the degree of Pseudomonas aeruginosa infection in chronic infected wounds |
733774 |
| 3.4.24.26 | industry |
A2 protease is usable for shrimp waste deproteinization in the process of chitin preparation, percent of protein removal after 3 h hydrolysis at 40°C with an enzyme/substrate ratio of 5 U/mg protein is about 75%. A2 proteolytic preparation also demonstrates powerful depilating capabilities of hair removal from bovine skin |
-, 717673 |
| 3.4.24.26 | industry |
potential application in the leather industry and as a therapeutic agent |
-, 753791 |
| 3.4.24.26 | industry |
pseudolysin is a biotechnologically important enzyme in the tanning industry |
735209 |
| 3.4.24.26 | medicine |
2-mercaptoacetyl-L-phenylalanyl-L-leucine represents a class of potent elastase inhibitors that might prove useful in the management of Pseudomonas aeruginosa infections |
665154 |
| 3.4.24.26 | medicine |
application of the inhibitors may be helpful in the management of corneal infections with Pseudomonas aeruginosa |
665250 |
| 3.4.24.26 | medicine |
enzyme can silence the function of proteinase-activated receptor-2 in the respiratory tract, thereby altering the host innate defense mechanisms and respiratory functions, and thus contributing to the setting of a disease like cystic fibrosis |
663600 |
| 3.4.24.26 | medicine |
Inflammation and consequent lung dysfunction are hallmarks of recurrent Pseudomonas aeruginosa infections in cystic fibrosis lungs. The continued presence of bacterial components, including PE, can evoke an ongoing host inflammatory response by induction of inflammatory cytokinines and chemokinines such as interleukin-8. Although this cytokinine is essential for an effective host defense, continuous neutrophil transmigration and degranulation will damage the lung tissue through neutrophil-derived proteases. Therefore, the use of specific antibody against Pseudomonas elastase as adjuvant therapy along with antibacterial agents can prove an effective approach in the treatment of chronic Pseudomonas aeruginosa infection. |
665182 |
| 3.4.24.26 | medicine |
phosphoramidon, the inhibitor of the enzyme, may prove beneficial in the treatment of Pseudomonas aeruginosa corneal infections |
664680 |
