EC Number   |
Application |
Reference |
|---|
   3.4.23.B1 | analysis |
enzyme is a specific marker in diagnosis of primary lung adenocarcinoma and to distinguish it from metastatic adenocarcinoma |
658694 |
| 3.4.23.B1 | analysis |
identification of suitable fluorogenic protease substrates for the pharmaceutically important napsin A by an easy, solid-phase combinatorial assay technology |
659577 |
| 3.4.23.B1 | diagnostics |
napsin A is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid carcinomas (EC). Napsin A levels in O-CCC and EM-CCC are analyzed and compared with levels in other nonmucinous ovarian carcinomas and EM-EC, respectively. But for diagnostics of napsin A expression in Arias-Stella reactions, napsin A expression is frequently present in foci of Arias-Stella reaction, a feature that they share with clear cell carcinomas. Therefore, Napsin A, in and of itself, is of minimal utility in this specific differential diagnostic scenario |
753774 |
| 3.4.23.B1 | diagnostics |
napsin A is an intracellular aspartic protease and biomarker of various malignancies like lung adenocarcinoma and ovarian clear cell carcinoma |
752689 |
| 3.4.23.B1 | diagnostics |
napsin A is another sensitive and specific marker for distinguishing ovarian clear cell tumors (especially adenocarcinomas) from other ovarian tumor |
754668 |
| 3.4.23.B1 | diagnostics |
napsin A is useful as a biomarker. Napsin A is as sensitive as calcitonin for C-cell neoplasms, but is less sensitive than thyroglobulin for follicular neoplasms. The tested markers are sensitive and, except for renal cell carcinoma (for Pax8, napsin A) and pulmonary adenocarcinoma (for napsin A), they are specific thyroid tumour markers |
754263 |
| 3.4.23.B1 | diagnostics |
napsin A, is useful as a marker of ovarian clear cell carcinoma, immunohistochemical study with 279 ovarian tumour samples, overview. Napsin A detection is specific but of intermediate sensitivity as a biomarker |
754994 |
| 3.4.23.B1 | medicine |
among 10 probes of surgically resected sclerosing haemangioma, all tumours have diffuse and intense expression of napsin A in cuboidal superficial cells, whereas the round interstitial component is completely negative in four cases, and shows focal granular cytoplasmic positivity in six cases |
717648 |
| 3.4.23.B1 | medicine |
enzyme is a specific marker in diagnosis of primary lung adenocarcinoma and to distinguish it from metastatic adenocarcinoma |
658356, 659838 |
| 3.4.23.B1 | medicine |
immunocytochemical markers for lung adenocarcinoma, identification of malignancy in effusions |
683396 |
