EC Number   |
Application |
Reference |
|---|
   3.4.17.17 | medicine |
TCP may be a target for developing novel therapeutic strategies against advanced stages of cancers. Inhibitors of TCP, by reversing abnormal detyrosinated tubulin accumulation in tumor cells, may impair tumor progression |
672915 |
| 3.4.17.17 | more |
cell-based assay for anti-microtubule compounds suitable for automation, based on the substrate properties of the tubulin-modifying enzymes TCP and TTL involved in the tubulin tyrosination cycle. Assay allows the identification, in a single screening campaign, of both microtubule-destabilizing and microtubule-stabilizing agents |
687835 |
| 3.4.17.17 | more |
interaction between MAP1B and TTL may have relevance to the dynamics of microtubule assembly and thus neuronal migration and axonogenesis |
686295 |
| 3.4.17.17 | more |
link between tubulinyl-Tyr carboxypeptidase and Nna1-like proteins |
686639 |
