EC Number   |
Application |
Reference |
|---|
   3.1.4.50 | diagnostics |
the enzyme might be a diagnostic predictive marker for abdominal aortic aneurysm |
729848 |
| 3.1.4.50 | medicine |
baseline GPI-PLD levels correlate with the change in insulin sensitivity in response to the low-fat diet, whereas baseline insulin sensitivity correlates with the change in insulin sensitivity in response to the lowcarbohydrate diet, plasma GPI-PLD may serve as a clinical tool to determine the effect of a low-fat diet on insulin sensitivity |
693991 |
| 3.1.4.50 | medicine |
enzyme activity is over 75% reduced in systemic inflammatory response syndrome, downregulation of enzyme could play an important role in the control of proinflammatory responses |
646477 |
| 3.1.4.50 | medicine |
enzyme may be involved in generation of circulating prognostic markers in cancer |
646493 |
| 3.1.4.50 | medicine |
glucose and insulin regulate enzyme mRNA levels |
646475 |
| 3.1.4.50 | medicine |
in a c-Myc transgenic disease model of liver cancer, serum GPI-PLD activity is increased 4fold in transgenic mice, while its tissue activity is reduced by 70% |
749993 |
| 3.1.4.50 | medicine |
in samples from steatohepatitis and hepatocellular carcinoma patients, serum GPI-PLD activity is increased 4fold, while its tissue activity is reduced by 60%. c-Myc influences GPI-AP signaling transcriptionally and posttranslationally and represses GPI-AP anti-proliferative signaling in tumors |
749993 |
| 3.1.4.50 | medicine |
insulin reduces serum enzyme levels in diabetics |
646488 |
| 3.1.4.50 | medicine |
patients with liver disease have lower activites, those with renal disease have higher activities than healthy controls |
646485 |
| 3.1.4.50 | medicine |
serum enzyme activity is positively correlated with inflammatory markers and counts of monocytes and stab cells |
646487 |
