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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6medicine enzyme displays higher activity in parasites cultured in low phosphate medium. Both promastigotes grown in low or high phosphate medium are capable of inducing the release of neutrophil extracellular traps from human neutrophils in a dose- and time-dependent manner. Parasites grown in low phosphate have 2.4 times higher survival rate than high phosphate promastigotes. Neutrophil extracellular traps disruption is prevented by the treatment of the parasites with inhibitor ammonium tetrathiomolybdate. Inhibition of the enzyme by 3'-AMP, 5'-GMP, or ammonium tetrathiomolybdate decreases promastigote survival upon interaction with neutrophils 729823
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6medicine leishmanial 3'-nucleotidase could become a target for chemotherapeutic attack because an enzyme with similar properties has not been detected in mammalian tissues -, 95088, 95091
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