EC Number   |
Application |
Reference |
|---|
   3.1.1.32 | analysis |
development of a spectrophotometric assay to measure, continuously and specifically, phospholipase A1 or phospholipase A2 activities using synthetic glycerophosphatidylcholines containing alpha-oleostearic acid. Substrates 1-alpha-eleostearoyl-2-octadecyl-rac-glycero-3-phosphocholine or 1-octadecyl-2-alpha-eleostearoyl-rac-glycero-3-phosphocholine differentiate, with excellent accuracy, between PLA1 and PLA2 activity |
751273 |
| 3.1.1.32 | degradation |
hydrolysis of nonpolar lipids, i.e. triacylglycerols, diacylglycerols and monoacylglycerols, when crude sunflower lecithin is treated with commercial product Lecitase VR Ultra. During the reaction, an acyl-migration phenomenon is observed. In 1 h of reaction the content of triacylglycerols decreases to 54%, while diacylglycerol and monoacylglycerol concentrations increase from 0.4 to 3.5 and from 1.9 to 6.5 g/100 g of crude lecithin, respectively. Along the reaction, different contents of glycerides can be achieved |
749788 |
| 3.1.1.32 | food industry |
the enzyme improves foaming stability and properties of skim milk and whey, implying that phospholipases can be useful tools for modifying the functionality of dairy products and ingredients |
680300 |
| 3.1.1.32 | industry |
enzyme can be used for degumming crude plant oil |
750141 |
| 3.1.1.32 | medicine |
acidotropic accumulation of cocaine in lysosomes inhibits acid phospholipase A1 and inactivates acid sphingomyelinase, inducing a mixed lysosomal lipidosis |
666965 |
| 3.1.1.32 | medicine |
homozygous mutation c.395dup/p.Gly133Argfs*26 in DDHD1 results in a complex form of hereditary spastic paraplegia associated with retinal dystrophy and a pattern of neurodegeneration with brain iron accumulation |
750476 |
| 3.1.1.32 | medicine |
may provide a valuable tool for diagnostic and therapeutic approaches in hymenoptera venom allergy. Recombinant Ves v 1 is an essential component to assess the sensitisation of individuals to yellow jacket venom and its recombinant availability complemented with Ves v 5 and phospholipase A2 from honeybee venom (Api m 1) allows for clear assignment of sensitisation patterns |
708202 |
| 3.1.1.32 | medicine |
role of enzyme in oncogenesis and metastasis of colorectal cancer. Tumor depth and hematogenous metastasis independently positively correlate with phospholipase A1 expression. High expression is associated with shorter disease-free survival, although it is not an independent predictive factor |
749586 |
| 3.1.1.32 | nutrition |
the enzyme improves foaming stability and properties of skim milk and whey, implying that phospholipases can be useful tools for modifying the functionality of dairy products and ingredients |
680300 |
| 3.1.1.32 | pharmacology |
the recombinant protein is allergenic in a biological assay as demonstrated by its capability to induce histamine release of wasp venom-sensitive basophils. The recombinant phospholipase A1 presents a good candidate for wasp venom immunotherapy |
716710 |
