EC Number |
Application |
Reference |
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2.5.1.66 | synthesis |
clavulanic acid intermediates: deoxygaunidinoproclavaminic acid, guanidinoproclavaminic acid, and dihydroclavaminic acid are heterologously produced in Streptomyces venezuelae recombinant using four sets of early genes from the clavulanic acid biosynthetic pathway |
742159 |
2.5.1.66 | synthesis |
in an industrial clavulanic acid-overproducer Streptomyces clavuligerus DEPA, carboxyethylarginine synthase (Ceas2), clavaldehyde dehydrogenase (Car) and carboxyethyl-arginine betalactam synthase (Bls2) are overrepesented, whereas the enzymes of two other secondary metabolites are underrepresented |
760210 |
2.5.1.66 | synthesis |
synthesis of clavulanic acid intermediates in Streptomyces venezuelae by expression of clavulanic acid biosynthesis genes carboxyethylarginine synthase (Ceas2), beta-lactam synthetase (Bls2), clavaminate synthase (Cas2), and proclavaminate amidinohydrolase (Pah2). The recombinant strain produces deoxygaunidinoproclavaminic acid, guanidinoproclavaminic acid, and dihydroclavaminic acid |
742159 |