2.4.1.331 | synthesis |
expression of NDP-glucose-synthase OleS, NDP-glucose-4, 6-dehydratase OleE, 2, 3-dehydratase OleV, 3, 5-epimerase OleL and 3-ketoreductase OleW in combination with elloramycin glycosyltransferase ElmGt in Streptomyces lividans results in accumulation of 8-demthyltetracenomycin C plus 8-demethyl-8-(4-dehydro)-alpha-L-olivosyl-tetracenomycin and 8-demethyl-8-alpha-L-olivosyl-tetracenomycin |
-, 729367 |