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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.251medicine PagP is not required for the initial colonization of the mouse respiratory tract by Bordetella bronchiseptica, but is required for persistence of the organism within this organ -, 734707
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.251synthesis deacylated lipid A, deacylated and palmitoylated lipid A, and palmitoylated lipid A species are generated in Escherichia coli cells heterologously expressing salmonellae lipid A 3-O-deacylase PagL and/or PagP, and then purified by sequential thin-layer chromatography. The purified lipid A species show m/z values that correspond to single lipid A species on mass spectrometry analysis. The modified lipid A species show reduced ability to induce cellular signaling through Toll-like receptor 4 734374
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