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Results 1 - 9 of 9
EC Number Application Commentary Reference
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2diagnostics GART expression is associated with glioma grade and high GART protein expression might be related to poor outcome 736945
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2diagnostics increased expression of glycinamide ribonucleotide transformylase is associated with a poor prognosis in hepatocellular carcinoma 736225
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine - 485731, 485735, 485737
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine glycinamide ribonucleotide transformylase has emerged as a productive target for antineoplastic therapeutic intervention 688291
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine glycinamide ribonucleotide transformylase is a validated target for cancer chemotherapy 685128
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine high GART expression is observed in glioma and is related to the grade of malignancy. GART overexpression is significantly associated with overall survival. Transfecting cells with GART-siRNA suppresses proliferation and enhances temozolomide-induced apoptosis in glioma cells 745966
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine inhibitor 5,10-dideazatetrahydrofolate is antiproliferate and cytotoxic against mammalian tumor cells in culture and have broad spectrum activity against transplantable mouse tumors and human tumor xenografts 485731, 485737
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine pharmacological importance, target enzyme for chemotherapy, development of novel antifolate drugs, to be used as anti-cancer drugs 485715, 485719, 485724, 485725, 485734, 485738, 485740, 485741
Show all pathways known for 2.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.2medicine target for structure-based drug design 485719
Results 1 - 9 of 9