EC Number   |
Application |
Reference |
|---|
   2.1.1.41 | agriculture |
construction of transgenic plants with modified sterol profile via recombinant sterol 24-C-methyltransferase shall protect crops against damage by insect infestation |
485330 |
| 2.1.1.41 | degradation |
active site of the yeast SMT has the necessary amino acids to generate products common to SMT catalysis of plants and protozoa, minor perturbations in the active site topography brought about by mutagenesis are sufficient to recognize new substrates |
671933 |
| 2.1.1.41 | drug development |
inhibition studies as a powerful approach to rational design of new anti-sleeping sickness chemotherapeutic drugs |
674757 |
| 2.1.1.41 | drug development |
newly synthesized azasterol derivates act at sites other than 24-SMT in Trypanosoma brucei |
-, 671372 |
| 2.1.1.41 | medicine |
SMT is a vaccine antigen for multiple forms of leishmaniasis |
706882 |
| 2.1.1.41 | medicine |
target for drug development against pneumonitis caused by this pathogen based on its unique substrate preference for lanosterol and 24-methylenelanosterol |
485335 |
| 2.1.1.41 | medicine |
the results indicate that SMT/MPL-SE can be an effective vaccine candidate for use against visceral leishmaniasis |
690178 |
| 2.1.1.41 | medicine |
vaccine development, visceral leishmaniasis |
690178 |
