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1.18.1.5
synthesis
omega-hydroxylation of medium-chain n-alkanes and primary alcohols by CYP153 enzymes from Mycobacterium marinum and Polaromonas sp. strain JS666 in presence of putidaredoxin and putidaredoxin reductase. Without putidaredoxin and putidaredoxin reductase, CYP153A16 shows negligible P450 oxidation activity towards n-octane
728422
1.18.1.5
synthesis
stereoselective production of pravastatin from avastatin by Escherichia coli co-expressing putidaredoxin reductase and putidaredoxin from Pseudomonas putida with cytochrome P450 105A3 from Streptomyces carbophilus. Improved active P450 expression leads to 4.1fold increase in pravastatin yield
727216
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