EC Number   |
Application |
Reference |
|---|
   1.16.1.8 | diagnostics |
the MTRR A66G polymorphism is a potential biomarker for cancer risk |
716185 |
| 1.16.1.8 | medicine |
cloning of the cDNA will permit the diagnostic characterization of cblE patients and investigation of the potential role of polymorphisms of this enzyme as a risk factor in hyperhomocysteinemia-linked vascular disease |
484889 |
| 1.16.1.8 | medicine |
study on association of natural polymorphisms I22M (A66G) and S175L (C524T) with bone mineral density and serum osteocalcin levels. No significant association between these two polymorphisms and bone mineral density and serum osteocalcin levels, but the 66G/524C haplotype affects bone turnover rate |
673482 |
| 1.16.1.8 | medicine |
the common variant I22M in methionine synthase reductase combined with low vitamin B12 increases risk for spina bifida |
659955 |
| 1.16.1.8 | medicine |
variant M22/S175 is a genetic determinant of plasma homocysteine levels and has been linked to premature coronary artery disease, Downs syndrome, and neural tube defects |
658055 |
