EC Number   |
Application |
Reference |
|---|
   1.14.17.3 | analysis |
enzyme PAM-dependent amidation has the potential to signal oxygen levels in the same range as the hypoxia-inducible factor (HIF) system |
745332 |
| 1.14.17.3 | medicine |
enzyme is an attractive target for anti-tumor compounds |
659916 |
| 1.14.17.3 | medicine |
PHM is a potential target for the development of inhibitors as drugs for the teratment of human disease |
696707 |
| 1.14.17.3 | medicine |
PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease |
696707 |
| 1.14.17.3 | medicine |
PHM is a potential target for the development of insecticides |
696707 |
| 1.14.17.3 | pharmacology |
enzyme is an attractive target for development of anti-tumor compounds |
659847 |
| 1.14.17.3 | synthesis |
usage of the recombinant PAM for insulin analogue amidation producing insulin glargine amide, an insulin derivative that shows a time/effect profile which is distinctly more flat and thus more advantageous than insulin glargine itself. The enzyme is used to modify glycine-extended A22(G)-B31(K)-B32(R) human insulin analogue (GKR). Hypoglycemic activity of amidated and non-amidated insulin is compared |
746370 |
