Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Application

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 6 of 6
EC Number Application Commentary Reference
Show all pathways known for 1.14.16.4Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.4analysis a Dugesia japonica TPH antibody is a useful marker for serotonergic neurons in planarians 689228
Show all pathways known for 1.14.16.4Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.4drug development substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel TPH1 inhibitors may provide novel treatments for gastrointestinal disorders associated with dysregulation of the serotonergic system, such as chemotherapy-induced emesis and irritable bowel syndrome 702586
Show all pathways known for 1.14.16.4Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.4medicine the serotonin transporter gene-linked promoter region 5-HTTLPR and tryptophan hydroxylase-2 genes act in concert to modulate the clinical response to citalopram among children and adolescents with depression and/or anxiety disorders 728032
Show all pathways known for 1.14.16.4Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.4medicine the two distinct serotonin systems in the brain (TPH2) and in the periphery (TPH1) can be targeted independently by pharmacological agents and new therapeutical options are available for psychiatric diseases on one side and disorders of haemostasis and the immune system on the other side 657881
Show all pathways known for 1.14.16.4Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.4medicine TPH2 is a good candidate gene for 5-hydroxytryptophan related psychiatric diseases such as bipolar affective disorders. The two distinnct serotonin systems in the brain (TPH2) and in the periphery (TPH1) can be targeted independently by pharmacological agents and new therapeutical options are available for psychiatric diseases on one side and disorders of haemostasis and the immune system on the other side 657881
Show all pathways known for 1.14.16.4Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.4more enhancement of L-tryptophan hydroxylation activity of L-phenylalanine 4-hydroxylase from Chromobacterium violaceum using information on the crystal structures of aromatic amino acid hydroxylases including TPH 699060
Results 1 - 6 of 6