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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.83drug development co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila 746441
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.83pharmacology co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila 746441
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.83synthesis artemisinic acid can be used as a promising elicitor, especially for the production of therapeutically important indole alkaloids 743890
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.83synthesis introduction of genes encoding strictosidine synthase (STR) and geraniol 8-hydroxylase (G10H), into Ophiorrhiza pumila hairy roots. Overexpression of individual G10H significantly improves camptothecin prdouction. Cooverexpression of G10H and STR genes causes a 56% increase on the yields of camptothecin. Camptothecin extracted from different lines shows similar anti-tumor activity 746441
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