EC Number |
Application |
Reference |
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1.13.11.63 | analysis |
BCMO function in mammalian cells is analyzed by a retinoic acid receptor assay, which responds to the metabolic conversion of beta-carotene to retinoic acid in vivo, this tool can be used to screen more active BCMO for the industrial and pharmacological purpose of retinal production from beta-carotene |
696901 |
1.13.11.63 | diagnostics |
genotyping AI rams for c.196C-T can be used in selection against the yellow fat trait |
714616 |
1.13.11.63 | medicine |
BCM gene expression in the liver and intestine might affect retinol levels in type 2 diabetes |
696512 |
1.13.11.63 | medicine |
changes in the metabolism of retinol and beta-carotene might have an important role in the protection against the development of nephrosis |
696511 |
1.13.11.63 | medicine |
Modulation of intestinal beta-carotene uptake and its conversion to vitamin A using specific fatty acids. Improved absorption and metabolism of beta-carotene by feeding mixed micelles with oleic acid or eicosapentanoic acid compared with linoleic acid |
675949 |
1.13.11.63 | synthesis |
production of all-trans-retinal by recombinant enzyme. Toluene is an optimal solvent for the dissolution of beta-carotene, and the optimal solution for the conversion reaction contains 2.4% (w/v) Tween 20, 0.15 U enzyme/ml, and 350 mg beta-carotene/l. Under these conditions, the enzyme produces 181 mg retinal/l after 20 h |
717408 |
1.13.11.63 | synthesis |
production of retinal from beta-carotene using recombinant enzyme. The optimum pH, temperature, substrate and detergent concentrations, and enzyme amount for effective retinal production are 9.0, 37°C, 200 mg per ml beta-carotene, 5% w/v Tween 40, and 0.2 U per ml enzyme, respectively. Under optimum conditions, the recombinant enzyme produces 72 mg per ml retinal in a 15 h reaction time, with a conversion yield of 36% w/w |
707236 |
1.13.11.63 | synthesis |
stepwise cleavage by BCO2, i.e. beta-carotene-9',10'-oxygenase, and BCO1 with beta-apo-10'-carotenol as an intermediate can provide a mechanism to tailor asymmetric carotenoids such as beta-cryptoxanthin for vitamin A production |
727965 |