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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.357drug development testosterone is converted to 5alpha-dihydrotestosterone, which is present at high concentrations in patients with castration resistant prostate cancer (CRPC). Inhibition of 17beta-HSD5 is therefore considered to be a promising therapy for treating CRPC. High-throughput inhibitor screening, overview 739797
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