EC Number   |
Application |
Reference |
|---|
    1.1.1.17 | agriculture |
Petunia hybrida (Hook) Vilm. cv. Mitchell is transformed with an Escherichia coli gene encoding mannitol 1-phosphate dehydrogenase. The high-mannitol containing lines are more tolerant of chilling stress than the low mannitol containing transgenic lines and wild-type. In the higher mannitol lines only 0.04% to 0.06% of the total osmotic potential generated from all solutes can be attributed to mannitol, thus its action is more like that of an osmoprotectant rather than an osmoregulator. Metabolic engineering of osmoprotectant synthesis pathways can be used to improve stress tolerance in horticultural crops |
669056 |
| 1.1.1.17 | analysis |
application of CRISPRi-dCas9 technique for gene repression |
-, 760419 |
| 1.1.1.17 | pharmacology |
inhibition of AfM1PDH might be a useful target for therapy of Aspergillus fumigatus infections |
722234 |
| 1.1.1.17 | synthesis |
hydrogen transfer from formate to D-fructose 6-phosphate, mediated by NAD(H) and catalyzed by a coupled enzyme system of purified Candida boidinii formate dehydrogenase and AfM1PDH, is used for the preparative synthesis of D-mannitol 1-phosphate or, by applying an analogous procedure using deuterio formate, the 5-[2H] derivative thereof, overview |
685964 |
| 1.1.1.17 | synthesis |
strategy for mannitol production in Lactococcus, most promising is overexpression of enzyme in a lactate-dehydrogenase deficient strain |
654280 |
