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Results 1 - 6 of 6
EC Number
Application
Commentary
Reference
synthesis
synthesis of oligoribonucleotides with defined sequence
medicine
regulated repression of the enzyme blocks editing, this repression is lethal in bloodforms of the parasite, indicating that editing is essential in the mammalian stage of the life cycle, the editing complex, which is present in all kinetoplastid parasites, may thus be a chemotherapeutic target
molecular biology
RNA ligase-mediated rapid amplification of cDNA ends (RLM-RACE); the properties of TS2126 RNA ligase 1 makes it very attractive for processes like adaptor ligation, and single-stranded solid phase gene synthesis
synthesis
RNA ligase-mediated method for the efficient creation of large, synthetic RNAs
synthesis
selective isotope labeling of RNA by introducing a labeled RNA segment via a two-step protocol, which uses T4 DNA ligase and T4 RNA ligase 1, and a one-pot protocol, which uses T4 RNA ligase 1 alone. Protection of termini is not required, provided segmentation sites can be chosen such that the segments fold into the target structure or target-like structures and thus are not trapped into stable alternate structures. Labeling protocols are generally applicable to large RNA molecules and can be extended to more than three segments
synthesis
efficient synthesis of 5' pre-adenylated DNA
Results 1 - 6 of 6