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EC Number
Application
Commentary
Reference
3.5.5.5
biotechnology
preparation of optically pure carboxylic acids
-
,
694107
3.5.5.5
synthesis
nitrilases are important industrial enzymes that convert nitriles directly into the corresponding carboxylic acids
-
,
719629
3.5.5.5
synthesis
recombinant cells expressing the enzyme are promising catalysts for the synthesis of stable chiral quaternary carbon centers from ketones
-
,
718648
3.5.5.5
synthesis
the enzyme is promising for the enantioretentive transformation of (S)-mandelonitrile
757638
3.5.5.5
synthesis
the whole cell arylacetonitrilase of Alcaligenes faecalis MTCC 12629 is employed to develop a bioprocess for the synthesis of 4-hydroxyphenylacetic acid from 4-hydroxyphenylacetonitrile. A fed batch process designed at 500 ml with five feedings of substrate results in 150 mM product formation using 18 U/ml whole cells nitrilase (16 mg/ml dcw) at 45°C and a volumetric and catalytic productivity of 23 g/l and 4.13 g/g dcw/h
-
,
758206
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