EC Number |
Application |
Reference |
---|
2.7.7.23 | synthesis |
biosynthesis of UDP-N-acetyl-alpha-D-glucosamine. As glycosylation is the most important modification for activating peptide drugs, the activated form of N-acetyl-alpha-D-glucosamine is thought to be important for future development of effective drugs |
-, 725308 |
2.7.7.23 | medicine |
GlmUMtb is a strong candidate for intervention measures against established tuberculosis infections |
-, 737150 |
2.7.7.23 | drug development |
N-acetylglucosamine-1-phosphate uridyltransferase (GlmU) is an attractive target for the development of antimicrobial agents |
741100 |
2.7.7.23 | medicine |
potential target for antibacterial agents |
643073, 643076 |
2.7.7.23 | drug development |
prokaryotic/microbial sugar nucleotidyl transferases are targets for design of selective inhibitors due to their different metal mechanisms compared to eukaryotes |
740866 |
2.7.7.23 | analysis |
quick and sensitive enzyme detection assay based on the diphosphatase-coupled colorimetric method with malachite green, and assay for glucosamine-1-phosphate N-acetyltransferase activity of the bifunctional enzyme, both applicable in microtitter plates |
-, 718708 |
2.7.7.23 | synthesis |
synthesis of UDP-N-acetyl-D-glucosamine |
643074 |
2.7.7.23 | drug development |
the enzyme GlmU is a target for development of antibacterial drugs |
720042 |
2.7.7.23 | drug development |
the enzyme is a potential drug target |
737391 |
2.7.7.23 | drug development |
the enzyme is a target for drugs treating the witches broom disease caused by Moniliophthora perniciosa in Theobroma cacao |
722022 |