EC Number   |
Natural Substrates |
|---|
   7.2.2.2 | ATP + H2O + Cd2+/in |
- |
| 7.2.2.2 | ATP + H2O + Cd2+/in |
transports glutathione-S-conjugates, like Cd-GS2, from the cytosol into the vacuole |
| 7.2.2.2 | ATP + H2O + Cd2+/in |
ABC transporter, DmHMT-1, confers tolerance to cadmium. DmHMT-1 and its yeast homolog, SpHMT-1, are not essential for vacuolar phytochelatin sequestration |
| 7.2.2.2 | ATP + H2O + Cd2+/in |
Cd2+ is a toxic environmental contaminant for biological systems, which can form complexes with reduced glutathione, and thus alter the intracellular redox state. In Saccharomyces cerevisiae, bis(glutathionato)cadmium, Cd-[GS]2, complexes can be removed from the cytosol and transported into the vacuole by a glutathione-conjugated pump, Ycf1p, which plays a role in Cd2+ detoxi?cation during respiratory metabolism and is correlated with the glutathione homeostasis, overview |
| 7.2.2.2 | ATP + H2O + Cd2+/in |
chloroplast envelope membrane protein OSA1, a member of the Abc1-like family, acts as a factor in cadmium and oxidative stress response, playing a role in the balance of oxidative stress |
| 7.2.2.2 | ATP + H2O + Cd2+/in |
the yeast ABC transporter belongs to the ABCC subfamily of ATP-binding cassette, ABC, transporters that rid cells of toxic endogenous and xenobiotic compounds, negative regulation of Ycf1p by phosphorylation within its N-terminal extension in addition to its ABC core domain and transports substrates in the form of glutathione conjugates |
| 7.2.2.2 | ATP + H2O + Cd2+/in |
ABC transporter, HMT-1, confers tolerance to cadmium. HMT-1 is not essential for vacuolar phytochelatin sequestration. HMT-1 either does not transport Cd-PC complexes or is not the principal Cd-PC/apoPC transporter |
| 7.2.2.2 | ATP + H2O + Cd2+[side 1] |
- |
| 7.2.2.2 | ATP + H2O + Cd2+[side 1] |
highest activity |
| 7.2.2.2 | ATP + H2O + Co2+[side 1] |
- |
