EC Number   |
Natural Substrates |
|---|
    6.3.2.3 | ATP + gamma-Glu-L-Cys + Gly |
- |
| 6.3.2.3 | ATP + gamma-Glu-L-Cys + Gly |
patients with hereditary glutathione synthetase deficiency suffer from haemolytic anaemia, 5-oxoprolinuria, metabolic acidosis, recurrent bacterial infections and various degrees of central nervous system dysfunction |
| 6.3.2.3 | ATP + gamma-Glu-L-Cys + Gly |
two NFE2 sites in the human GSS promoter play important roles in the basal expression of glutathione synthetase. The glutathione synthetase gene expression is also regulated by Nrf2 |
| 6.3.2.3 | ATP + gamma-Glu-L-Cys + Gly |
glutathione biosynthesis |
| 6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly |
- |
| 6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly |
ApoE-deficient mice show reduced enzyme expression and activity, genetic regulation mechanism, overview |
| 6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly |
final step in glutathione biosynthesis |
| 6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly |
final step of glutathione biosynthesis |
| 6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly |
gene is regulated by stresses via the Atf1-Spc-1-Wis1 signal pathway |
| 6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly |
second step in the biosynthesis of glutahione |
